A scaffold consists of an architecture of materials, precisely designed to serve a function. As described by many, “form follows function”. Osteopore scaffolds are designed based on this principle.
The unique laydown pattern of Osteopore scaffolds creates interconnected pores in 3D. Interconnectivity is very important to ensure sufficient nutrient flow.
Bioresorbable refers to the act of being absorbed by the body, without adverse events. To understand this better, we need to understand how our body works. During the implantation of foreign materials into our body, a period of inflammation follows, and depending on the interactions between the material and our immune system, inflammation may be acute, or chronic. To understand inflammation more, please click here**. The more irritable the implanted material is, the more likely inflammation will be prolonged.
**Inflammation is not undesirable; prolonged inflammation is undesirable. In fact, inflammation helps the healing process. According to Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, “For wounds to heal we need controlled inflammation, not too much, and not too little,"
Yes! Our products have been used in clincics for over 10 years and counting, and we do not have records of adverse events.
The process of bioresoption begins with the degradation of the implant, which may be initiated by many factors, including local pH conditions, enzymatic activities, and macrophage activation, all of these which make up the inflammatory environment.
At the onset of degradation, small segments of the implant will be slowly removed, and depending on the chemical nature and compatibility of these degradation by-products, they may be taken up into the body’s important, natural metabolic cycle known as the citric acid cycle.
Yes! PCL is resorbable, its final degradation products are carbon dioxide and water.
The Osteopore PCL Scaffold™ is a bone void filler. The shape of the Osteopore PCL Scaffold™ conforms to the defect, thus maximizing direct contact with viable host bone. It is intended for use in the repair of neurosurgical burr holes, craniotomy cuts and other cranial defects.
Osteopore is able to meet your requirements for customization.
Osteopore has a strong research team that has a solid foundation in medical device design. We are always keen to develop new products that benefit patients. Please check back for updates on our latest/upcoming products.